黄海艳

  • 职    称:副教授

  • 电子邮箱:haiyanhuang@shmu.edu.cn

  • 办公地点:上海市徐汇区东安路131号科研二号楼

  • 教育经历

  • 工作经历

  • 研究方向

  • 科研项目

  • 课程讲授

  • 代表性论著

  • 2002.09 — 2005.07 复旦大学, 生物化学与分子生物学, 博士

  • 1998.09— 2001.07 中国医科大学, 临床药理学, 硕士

  • 1993.09—1998-07 中国医科大学, 护理学, 学士

  • 2012.12—至今     williamhill官网生物化学与分子生物学系硕士生导师

  • 2009.12—至今     williamhill官网生物化学与分子生物学系副教授

  • 2006.01—2009.11  williamhill官网生物化学与分子生物学系讲师

  • 细胞微环境对多潜能干细胞定向分化和代谢综合征的作用研究

  • 脂肪组织与肝脏的对话研究

  • 2021,国家自然科学基金面上项目,“脂肪组织赖氨酰氧化酶对非酒精性脂肪肝的作用研究”,主持

  • 2018,国家自然科学基金面上项目,“赖氨酰氧化酶重塑脂肪组织炎症微环境的机制研究”,主持

  • 2013,国家自然科学基金面上项目,“ADAMTS1改变细胞微环境对脂肪细胞定向的作用及机制”,主持

  • 2012,国家自然科学基金面上项目,“EMT对间充质干细胞的募集和定向为前棕色脂肪细胞的作用及机制”,主持

本科生课程:

  • 生物化学、人体分子与细胞、Biochemistry、PBL

研究生课程:

  • 医用分子遗传学

  1. Qi-Xiang Ma#, Wen-Ying Zhu, Xiao-Chen Lu, Duo Jiang, Feng Xu, Jin-Tao Li, Lei Zhang, Ying-Li Wu, Zheng-Jun Chen, Miao Yin*, Hai-Yan Huang*, Qun-Ying Lei*. BCAA–BCKA axis regulates WAT browning through acetylation of PRDM16. Nature Metabolism, DOI:10.1038/s42255-021-00520-6, 2022.

  2. Chun Xing#, Duo Jiang#, Yang Liu, Qiqun Tang, Haiyan Huang*. Lysyl oxidase inhibition enhances browning of white adipose tissue and adaptive thermogenesis. Genes & Diseases, 9, 140-150, 2022.

  3. Chen SZ#, Ning LF, Xu X, Jiang WY, Xing C, Jia WP, Chen XL, Tang QQ*, Huang HY*. The miR-181d-regulated metalloproteinase Adamts1 enzymatically impairs adipogenesis via ECM remodeling. Cell Death Differ, 23(11), 1778-1791, 2016.

  4. Huang H#, Song TJ#, Li X, Hu L, He Q, Liu M, Lane MD, Tang QQ*. BMP signaling pathway is required for commitment of C3H10T1/2 pluripotent stem cells to the adipocyte lineage. Proc Natl Acad Sci U S A, 106(31), 12670-5, 2009 .

  5. Jiang WY#, Xing C#, Wang HW,Wang W, Chen SZ, Ning LF, Xu X, Tang QQ, Huang HY*. A Lox/CHOP-10 crosstalk governs osteogenic and adipogenic cell fate by MSCs. J Cell Mol Med, 22(10), 5097-5108, 2018.

  6. Huang HY#*, Zhang WT#, Jiang WY, Chen SZ, Liu Y, Ge X, Li X, Dang YJ, Wen B, Liu XH, Lu HJ, Tang QQ*.RhoGDIβ Inhibits Bone Morphogenetic Protein 4 (BMP4)-induced Adipocyte Lineage Commitment and Favors Smooth Muscle-like Cell Differentiation. J Biol Chem, 290(17), 11119-29, 2015.

  7. Chen SZ#, Xu X, Ning LF, Jiang WY, Xing C, Tang QQ, Huang HY*. miR-27 impairs the adipogenic lineage commitment via targeting lysyl oxidase. Obesity, 23(12), 2445–2453, 2015.

  8. Huang HY#, Chen SZ, Zhang WT, Wang SS, Liu Y, Li X, Sun X, Li YM, Wen B, Lei QY, Tang QQ*. Induction of EMT-like response by BMP4 via up-regulation of lysyl oxidase is required for adipocyte lineage commitment. Stem Cell Res, 10(3), 278-87, 2013.

  9. Huang HY#, Hu LL#, Song TJ, Li X, He Q, Sun X, Li YM, Lu HJ, Yang PY, Tang QQ*. Involvement of cytoskeleton-associated proteins in the commitment of C3H10T1/2 pluripotent stem cells to adipocyte lineage induced by BMP2/4. Mol Cell Proteomics, 10(1), M110.002691, 2011.

  10. Wang SS#, Huang HY*, Chen SZ, Li X, Liu Y, Zhang WT, Tang QQ*. Early growth response 2 (Egr2) plays opposing roles in committing C3H10T1/2 stem cells to adipocytes and smooth muscle-like cells. Int J Biochem Cell Biol, 45(8), 1825-32, 2013.