王松梅

  • 职    称:副教授

  • 联系电话:021-54237330

  • 电子邮箱:smwang2@fudan.edu.cn

  • 办公地点:上海市徐汇区东安路131号东5号楼405室

  • 教育经历

  • 工作经历

  • 获得奖项

  • 研究方向

  • 科研项目

  • 课程讲授

  • 学术兼职

  • 代表性论著

  • 代表性专利

  • 1987.9-1992.6安徽医科大学卫生系本科生

  • 1994.9-1997.6上海医科大学生物物理学专业硕士研究生

  • 2000.9-2004.6复旦大学生物化学与分子生物学专业博士研究生

  • 1992.7-1994.8安徽省蚌埠市职业病防治所医师

  • 1997.7-2000.6上海医科大学生物物理学系助教

  • 2000.6-目前williamhill官网医学实验教学中心讲师、副教授

  • 2011.6-2012.8美国Johns Hopkins医学院访问学者

  • 2001.6上海市科技进步三等奖

  • 2016.中华医学会百篇优秀论文三等奖

  • 2013上海市教委本科重点课程

  • 2008复旦大学研究生教学成果二等奖

  • 2007复旦大学教学成果三等奖

  • 肿瘤分子生物学。血液系统恶性肿瘤的发生机制及治疗;肝癌的免疫微环境及抗粘附小分子肽的抑瘤作用

  • 病毒性腹泻研究。我国5岁以下儿童的腹泻感染谱;诺如病毒和轮状病毒的感染机制及疫苗研制;DNA疫苗研究。

  • 科技部十四五重点专项,病原学与防疫技术体系研究,2022.1-2026.12. 子任务负责人

  • 国家科技重大专项课题,重大新药创制. 子课题,基于重组病毒样颗粒技术的多价诺如病毒新型疫苗”(2018ZX09739002-006). 2018.01-2020.12. 子课题负责人

  • 国家自然科学基金面上项目:淫羊藿素下调EB病毒LMP1表达抑制鼻型NK/T细胞淋巴瘤的作用及机制. 项目批准号:81470352,2014,主持

本科生课程:

  • 分子生物学理论与实验、基础医学研究入门、核心实验技术、医学与现代分子生物学技术、医学生物学研究技术与实验、

研究生课程:

  • 分子生物学技术(一)、分子生物学技术(二)、组学技术

  • 2014.10-2020.10上海市生物物理学会理事、副秘书长

  • 2020.10-目前上海市生物物理学会副秘书长兼日常办公室副主任

  • 2015.-目前内科理论与实践杂志编委

  1. Canjing Zhang*, Huiwen Xu*, Xianxian Sui, Lina Chen, Bobin Chen, Haozhen Lv, Songmei Wang# Xuanyi Wang#. Icaritin inhibits PLK1 to activate DNA damage response in NK/T cell lymphoma and increases sensitivity to combined gemcitabine, oxaliplatin, and L-asparaginase (GELOX). Molecular Therapy–Oncolytics, 2022(on line)

  2. Hong-Lu Zhou 1,† , Li-Na Chen 1,†, Song-Mei Wang 2,†, Ming Tan 3,4 , Chao Qiu 1 , Tian-Yi Qiu 5,* and Xuan-Yi Wang. Prevalence and Evolution of Noroviruses between 1966 and 2019, Implications for Vaccine Design. Pathogens. 10:1012, 2021

  3. Zhou HL*, Bessey T*, Wang SM*, Mo ZJ*, Barclay L, Wang JX, Zhang CJ, Ma JC, Qiu C, Zhao G, Li RC, Zhao YL, Jiang BM#, Wang XY#. Burden and Etiology of Moderate and Severe Diarrhea in Children Less than 5 Years of Age Living in North and South of China: Prospective, Population-based Surveillance. Gut Pathogens. 13-33, 2021

  4. Jin-Xia Wang*, Li-Na Chen*, Can-Jing Zhang*, Hong-Lu Zhou, Yan-Hong Zhang, Xin-Jiang Zhang, Zhi-Yong Hao, Chao Qiu, Jing-Chen Ma, Yu-Liang Zhao, Weiming Zhong, Ming Tand, Xi Jiang, Song-Mei Wang#, Xuan-Yi Wang#. Genetic susceptibility to rotavirus infection in Chinese children: A population-based case-control study. Human Vaccines & Immunotherapeutics. 17(6):1803-1810, 2021

  5. Zhou HL*, Wang SM*, von Seidlein L, Wang XY. The epidemiology of norovirus gastroenteritis in China: disease burden and distribution of genotypes . Front Med. 14(1): 1-7, 2020

  6. Wang JX, Zhou HL, Mo ZJ, Wang SM, Hao ZY, Li Y, Zhen SS, Zhang CJ, Zhang XJ, Ma JC, Qiu C, Zhao G, Jiang B, Jiang X, Li RC, Zhao YL, Wang XY. Burden of viral gastroenteritis in children living in rural China: Population-based surveillance [J]. Int J Infect Dis. 90: 151-60, 2020

  7. Xianxian Sui*, Canjing Zhang*, Yudong Jiang, Jianan Zhou, Chen Xu, Feng Tang, Bobin Chen, Huiwen Xu, Songmei Wang#, Xuanyi Wang#. Resveratrol activates DNA damage response through inhibition of polo-like kinase 1 (PLK1) in natural killer/T cell lymphoma. Annals of Translational Medicine. 8(11):688-701, 2020

  8. Jianan Zhou, Canjing Zhang, Xianxian Sui, Shengxuan Cao, Feng Tang, Shuhui Sun, Songmei Wang#, Bobin Chen#. Histone deacetylase inhibitor chidamide induces growth inhibition and apoptosis in NK/T lymphoma cells through ATM-Chk2-p53-p21 signalling pathway. Invest New Drugs. 36(4): 571-580, 2018

  9. Xianxian Sui, Canjing Zhang, Jianan Zhou, Shengxuan Cao, Chen Xu, Feng Tang, Xiuling Zhi, Bobin Chen, Songmei Wang# and Lianhua Yin#. Resveratrol inhibits Extranodal NK/T cell lymphoma through activation of DNA damage response pathway. Journal of experimental and clinical cancer research. 36(1):133, 2017

  10. Ting Wu*, Songmei Wang*, Jinfeng Wu, Zhiguang Lin, Xianxian Sui, Xiaoping Xu, Norio Shimizu, Bobin Chen# and Xuanyi Wang#. Icaritin induces lytic cytotoxicity in extranodal NK/T-cell lymphoma. Journal of Experimental and Clinical Cancer Research. 34:17-27, 2015

  1. 申请专利. 王松梅,汪萱怡,张灿晶,陈丽娜,隋鲜鲜,吴婷,徐慧雯. 一种NK/T淋巴瘤小鼠模型的建立方法. 2020.9.30, 中国,202011063506.9

  2. 授权发明专利. 陈波斌、吴婷、王松梅、吴金峰、许小平、汪萱怡, 淫羊藿素在制备抗NK/T细胞淋巴瘤药物中的用途, 2017.10.10, 中国, ZL201410198524.6