钱淑文

  • 职    称:教授

  • 电    话:021-54237571

  • 电子邮箱:shuwenqian@fudan.edu.cn

  • 办公地点:上海市徐汇区东安路131号科研二号楼A4-030

  • 教育经历

  • 工作经历

  • 获得奖项

  • 研究方向

  • 科研项目

  • 课程讲授

  • 代表性论著

  • 1996.09—2001.07  苏州大学医学院 本科生

  • 2001.09—2004.07  复旦大学医学院 硕士研究生

  • 2006.09—2009.07  复旦大学生物医学研究院 博士研究生

  • 2004.08—2006.08  上海市南方模式生物研究中心 助理研究员

  • 2009.07—2014.12  williamhill官网 助理研究员

  • 2014.12—至今    williamhill官网 副研究员

  • 2016,自然科学二等奖,教育部

  • 脂肪发育和代谢功能

  • 2016,国家自然科学基金面上项目,“BMP4通过巨噬细胞调控米色脂肪生成的作用机制研究”,主持

  • 2012,国家自然科学基金青年项目,“骨形成蛋白 4 通过影响脂肪细胞脂代谢调节胰岛素敏感的作用研究”,主持

本科生课程:

  • 正常人体形态和功能学、MBBS生物化学实验

  1. Wang YN, Tang Y, He Z, Ma H, Wang L, Liu Y, Yang Q, Pan D, Zhu C, Qian S*, Tang QQ*. Slit3 secreted from M2-like macrophages increases sympathetic activity and thermogenesis in adipose tissue. Nat Metab. 2021; 3(11):1536-1551.

  2. Mu W#, Qian S#, Song Y, Yang L, Song S, Yang Q, Liu H, Liu Y, Pan D, Tang Y,Tang QQ. BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis. Redox Biol. 2021; 43:101979.

  3. Qian S, Tang Y, Tang QQ. Adipose tissue plasticity and the pleiotropic roles of BMP signaling. J Biol Chem. 2021; 296:100678. Review.

  4. Zou Y, Wang YN, Ma H, He ZH, Tang Y, Guo L, Liu Y, Ding M, Qian SW*, Tang QQ*. SCD1 promotes lipid mobilization in subcutaneous white adipose tissue. J Lipid Res. 2020;61(12):1589-1604.

  5. Qian S#, Pan J#, Su Y#, Tang Y, Wang Y, Zou Y, Zhao Y, Ma H, Zhang Y, Liu Y, Guo L, Tang QQ. BMPR2 promotes fatty acid oxidation and protects white adipocytes from cell death in mice. Commun Biol. 2020;3(1):200.

  6. Zhao YX, Pan JB, Wang YN, Zou Y, Guo L, Tang QQ*, Qian SW*. Stimulation of histamine H4 receptor participates in cold-induced browning of subcutaneous white adipose tissue. Am J Physiol Endocrinol Metab. 2019;317(6):E1158-E1171.

  7. Qian SW#, Wu MY#, Wang YN, Zhao YX, Zou Y, Pan JB, Tang Y, Liu Y, Guo L, Tang QQ. BMP4 facilitates beige fat biogenesis via regulating adipose tissue macrophages. J Mol Cell Biol. 2019;11(1):14-25.

  8. Shu-wen Qian#, Yan Liu#, Jue Wang, Ji-chang Nie, Meng-yuan Wu, Yan Tang, Ya-Xin Zhao, Xi Li, Hai-yan Huang, Liang Guo, Xi-shi Liu, Cong-jian Xu, Qi-Qun Tang. BMP4 cross-talks with estrogen/ERα signaling to regulate adiposity and glucose metabolism in females. EBioMedicine, 2016;11:91-100.

  9. Yan Tang, Shu-wen Qian*, Jue Wang, Meng-yuan Wu, Ping Lu, Xi Li, Hai-yan Huang, Liang Guo, Xia Sun, Cong-jian Xu, Qi-qun Tang*. BMP4 mediates the interplay between adipogenesis and angiogenesis during subcutaneous white adipose tissue expansion. Journal of Molecular Cell Biology, 2016;8(4):302-12.

  10. Shu-wen Qian, Yan Tang, Xi Li, Yuan Liu, You-you Zhang, Hai-yan Huang, Rui-Dan Xue, Hao-yong Yu, Liang Guo, Hui-di Gao, Yan Liu, Xia Sun, Yi-ming Li, Wei-Ping Jia, Qi-qun Tang. BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis. Proc Natl Acad Sci U S A. 2013; 110(9):E798-807.